Growth hormone deficiency (GHD) is a disorder that may affect both children and adults. The underlying cause is insufficient growth hormone production by the pituitary gland, which results in slower than normal growth for children. Children need growth hormone in order to grow normally and deficiency of the hormone may result in short stature, low growth rate, delayed tooth development, and delayed onset of puberty. Growth hormone deficiency may also affect adults and result in a variety of symptoms including reduced muscle and bone strength, larger waist size, reduced muscle and increased fat in body composition, and high cholesterol. It can even result in psychological symptoms such as depression, tiredness, and lack of motivation.

Growth hormone therapy can help patients who don’t make enough growth hormone on their own. Although there are several FDA-approved hGH preparations they all require daily subcutaneous injections. These injections are invasive and painful making the administration very inconvenient to patients and affecting medication adherence. This is an even greater challenge for children who are more sensitive to the way of administration.

Delpor’s DLP-202 product is a long acting system for the delivery of human growth hormone. The system is designed to deliver therapeutic levels of growth hormone for a period of 3 months. The device can be implanted during a simple 10 minute in-office procedure using local anesthetic. One procedure is expected to replace 90 injections and offer a safe and convenient alternative to patients.